Antabuse Medication Reviews
- • Potential consumers of Antabuse-like drugs
- • Overcoming Alcohol Addiction
- • How does the Antabuse drug work?
- • Antabuse Contraindications and Limitations
- • Antabuse-alcohol tests and drugs based on gels
- • The effect of the Antabuse drug
As the user of the drug "Antabuse" can be a large group of people suffering from chronic alcoholism. Chronic alcoholism, it's an alcoholic illness or alcoholic substance abuse, is a painful attraction to alcohol abuse, based on physical and mental dependence. Alcoholism today is the most common form of substance abuse, characterized by the constant use of ethyl-containing drinks, which entails a lot of mental and physical disorders, personal changes.
Potential consumers of Antabuse-like drugs
Tablets "Antabuse" are prescribed only by a doctor at one or another stage of the disease. And the chronic alcoholism begins innocently enough - a person first takes a random dose of alcohol, then the use becomes systematic, and the doses all increase. Such conditions under the name of everyday drunkenness can last from 2-5 to 10-15 years (on average about 5-10). Household drunkenness, more common in men, then goes directly to chronic alcoholism, in which several degrees of severity of the disease are distinguished.
"Antabuse", as a rule, is not applied at the first stage of the development of the disease. Here, the human body reacts to alcohol by the absence of vomiting when overdosing and mixing, there is already a syndrome of increasing tolerance - the need for increasingly substantial alcohol doses, abusing suffering from alcoholic palimpsests - does not remember what it was the day before, during the libations, can drink several times a week , often several days in a row, which indicates the transition to the second stage.
Medications similar to Antabuse in action, such as Litonit, Tempozil, herbal decoction, sheep, cefoperazone, latamoxef, and pyroxene, are often used in the next stage of the disease when the alcoholic develops withdrawal symptoms like withdrawal symptoms. Such a person already constantly strives for drinking, often consumes alcohol alone, in a company of casual acquaintances.
Alcohol intoxication manifests itself in malice, fault-finding, discontent, sleep disorders. The patient can stay on his feet and speak quite articulate even with high doses of alcohol (the body is used to it). The amount of alcohol at this stage reaches the maximum volume, with liquor begin to "recover" in the morning to remove the hangover.
Overcoming Alcohol Addiction
The second stage of alcoholism is accompanied by such diseases as asthenic and vasomotor disorders, tachycardia, headache, chilliness, pain in the liver, upset stomach, loss of appetite. Behavior is characterized by suspicion, a sense of fear, depressive assessments. Sleep sick often filled with loud sounds, because of what he wakes up in fear and can not understand where he is and what happens.
In the second stage, abusers can go into months for drinking or suffer from pseudo-snags within 3-4 or 7-10 days. Pseudo-sores are explained by the fact that the patient is distracted from drunkenness for the sake of work, family or because of cramping in money, but then continues to drink, because. the craving for ethyl alcohol is already pronounced.
"Antabuse" is often used in the third stage of chronic alcoholism when the drinking person reduces the amount of alcohol since intoxication is obtained from smaller doses of drinks (for example, instead of vodka they drink fortified wines). A feature of this stage is that binges often depend on changing physical or mental health.
A small amount of alcohol at the beginning of drinking is accompanied by the continued use of large doses for several days. In each subsequent day, the reaction of intoxication comes from a smaller quantity of the drink, while the number of failures in the somatic state increases, which makes it impossible to continue drinking further.
At this stage binges last about a week, intoxication is shallow, the mental state is benign, passive. But here there are serious disruptions in the work of the brain, cardiovascular system, digestive tract, so people drink less because they have almost no health.
How does the Antabuse drug work?
Treatment with "Antabuse" should start much earlier, if the drug is suitable for a particular patient. The active ingredient of the drug is a component of disulfiram, ingredients such as talc, povidone and microcrystalline cellulose, magnesium stearate and silica (colloidal), tartaric acid and corn starch are also present.
The principle of functioning of the Antabuse is based on the fact that it causes the accumulation of such an intermediate product as acetaldehyde, which, when taking alcohol, gives a state close to the thermal one, and this implies a rejection of binge and suppression of attraction to it.
The influence of "Antabuse" on the body is such that without the use of alcohol it does not affect the operation of the basic systems. However, in a mixture with alcohol tablets, reactions that produce fever, headache, chills, a drop in pressure, a feeling of fear, trigger the conditioned reaction to the aversion to alcohol. Such signs appear at the smallest doses of alcoholic beverages.
The drug is more than serious, therefore, the doctor explains the recommendations for its use of alcohol abusers. The medicine cannot be given to the patient in secret from him, as a joint reaction can cause a violation of breathing, loss of consciousness and even death.
With the appointment of "Antabuse", a detailed examination of the body is conducted, alcohol tests are carried out, the patient confirms that he wants to really give up alcohol. This is very important, because, After a long reception, cancellation and resumption of alcohol intake, hallucinosis, psychosis, nervous and cardiovascular diseases may occur, the risk of strokes and heart attacks increases.
Antabuse Contraindications and Limitations
Such pills cannot be taken by patients with certain health problems, which include:
- Kidney disease.
- Mental illness, epilepsy, convulsive conditions.
- Diabetes mellitus and diseases of the hematopoietic organs.
- Breastfeeding and the period of bearing a child.
- Polyneuritis of any genesis.
- Thyrotoxicosis and exacerbation of ulcer diseases.
- Hepatic insufficiency, emphysema, and asthma.
- Diseases of the nervous and cardiovascular systems in severe form, etc.
The description of the drug indicates that it can be used for individual intolerance, for elderly patients, after a violation of the blood circulation of the brain, stomach and duodenal ulcer in remission, after previously experienced psychoses caused by taking the medication.
"Antabuse" is available in such forms as tablets, a special complex "Esperal" or in the form of a gel for intramuscular injection. "Esperal" is a complex of tablets in a special shell sealed in a special bottle. They allow you to create a certain depot of disulfiram in the body, which will work when drinking ethyl-containing drinks.
The drug is sutured into fatty tissue/muscle (usually the gluteal or armpit) under local anesthesia. The validity period is set for each patient individually and depends on the number of sewn capsules. Reviews indicate that the greatest psychological effect is precisely the installation of the Esperal because all manipulations are carried out in the surgical department, which increases the importance of the procedure.
Gel on the basis of "Esperal" is administered intravenously or subcutaneously. The validity period is from 3 months to 3 years.
Antabuse-alcohol tests and drugs based on gels
Tablets of this medicine are issued in the effervescent form, 200 mg (100 pieces per pack) or 0.4 g (50 pcs.). Admission is prescribed from 200 to 500 mg per day, according to a strictly individual scheme, 1 or 2 times during the day.
After taking the medication for one week, the patient is prescribed the next dose of the drug in the morning, after 8-9 hours they offer to drink about 20 g of vodka and check the reaction. If it is not enough, the dose of alcohol is increased to determine the required amount of the drug to produce a conditioned reaction to alcohol. In the future, the patient can take the medicine for 1 to 3 years as a maintenance therapy (about 200 mg per day, set individually).
The use of the gel involves injecting the patient, most often under the shoulder blade. Depending on the individual characteristics, a dose is chosen that will last from 1 year to 3 years. In the event that the patient is assigned "Disulfiram-gel," he can have a prolonged effect for up to 5 years.
The peculiarity of this formulation of drugs is a slow withdrawal of the drug naturally, therefore, as a rule, the gel works almost always the time that was declared at the appointment.
The effect of the Antabuse drug and the lethal outcome
Reviews about this drug are mainly offered by doctors who observe patients being treated. They mention that when taking alcohol samples in people with chronic alcoholism in the latter stages of the reaction was less pronounced. But they included insomnia, fear, sometimes depersonalization (for example, sensations of loss of a head or other part of a body), tearfulness, desire to refuse treatment.
That is, all the signs of acute psychosis were manifested. Someone from patients with less "experience" suffered memory loss for a long period (dozens of years), hallucinations, delusions appeared. But almost always such phenomena completely passed after the completion of the verification of alcoholics reactions to Antabuse-like drugs and complex treatment (detoxification, therapeutic sleep, training with a psychologist-psychotherapist, etc.). The average duration of Antabuse psychosis can be from 5 to 21-25 days.
Tablets and other forms of Antabuse-containing drugs taken by the patient, with the use of even the smallest doses of alcohol (5-10 g) in half a minute give a heaviness in the head, a loss of ability to move, a feeling of paralysis of the airways. To improve the condition of a drunkard or even save him from death is possible only if you know exactly when, what medicine, and in what doses it was delivered to him.
In clinical conditions for poisoning with acetaldehyde, a 1% aqueous methylene blue solution is used, which only removes the effect of the poison on the tissue, but does not remove the disulfiram from the body itself, and the signs of poisoning will manifest in the same measure with the subsequent drinking of alcoholic beverages.
Councils of doctors are reduced to the fact that it is better not to take risks, taking alcohol during the term of the drug. It can cost a person's life.